Article

Subtype-specific downregulation of voltage-gated sodium channels shapes neuronal responses to neuroinflammation

2026-08-27

Abstract excerpt

Epilepsy is one of the most common neurological disorders, affecting more than 50 million people worldwide. Among the genetic etiologies of epilepsy, variants in genes coding for ion channels are vastly represented and characterized. Notably, loss-of-function (LoF) mutations in voltage-gated sodium channels (NaV) genes can result in a wide range of phenotypes including West syndrome, autism spectrum disorder, or D...

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Literature Corpus work: 4759e259-2bcc-567b-8614-066fc3f7e8e7
DOI: 10.64898/2026.08.24.746613

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