Article

The role of the gut microbiota in patients with Kleefstra syndrome

2022-02-07

Abstract excerpt

Kleefstra Syndrome (KS) is a rare monogenetic syndrome, caused by haploinsufficiency of the EHMT1 gene, an important regulator of neurodevelopment. The clinical features of KS include intellectual disability, autistic behavior and gastrointestinal problems. The gut microbiota may constitute a, yet unexplored, mechanism underlying clinical variation, as they are an important modifier of the gut-brain-axis. To test...

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Literature Corpus work: 4721a389-282f-5b4a-9e2f-530d2bc9a506
DOI: 10.1101/2022.02.04.478662

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