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Bacterial genomic structural variations in children with autism serve as diagnostic biomarkers

26 Feb 2026

Abstract excerpt

Background Gut microbiota dysbiosis is linked to autism spectrum disorder (ASD) in children. However, the role of bacterial genomic structural variations (SVs) in ASD remains largely unexplored. Objective We aimed to identify bacterial SVs associated with ASD and explore their mechanistic role and clinical application. Design We collected faecal metagenomes from 452 children (261 ASD, 191 neurotypical) across an...

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PMID: 41748159
DOI: 10.1136/gutjnl-2025-337280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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