Article

A Familial Chromosome 4p16.3 Terminal Microdeletion That Does Not Cause Wolf-Hirschhorn (4p-) syndrome

2024-07-16

Abstract excerpt

<title>Abstract</title> <p>Chromosome 4p16.3 microdeletions are known to cause Wolf–Hirschhorn syndrome (WHS), which is characterized by a distinct craniofacial gestalt and multiple congenital malformations. The 4p16.3 region encompasses WHS critical region 1 (WHSCR1) and 2 (WHSCR2). The WHSCR contains several genes that have been implicated in the WHS phenotype including: WHS candidate 1 [<italic>WHSC1</italic>(...

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Literature Corpus work: 4543f46e-0d13-58fe-a972-5ad0c3cb619a
DOI: 10.21203/rs.3.rs-4566567/v1

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