Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Update on the clinical features and natural history of Wolf-Hirschhorn (4p-) syndrome: experience with 87 patients and recommendations for routine health supervision.

American journal of medical genetics. Part C, Seminars in medical genetics - 15 Nov 2008

Battaglia Agatino, Filippi Tiziana, Carey John C

Abstract excerpt

Wolf-Hirschhorn syndrome (WHS) is a well-known multiple congenital anomalies/mental retardation syndrome, firstly described in 1961 by Cooper and Hirschhorn. Its frequency is estimated as 1/50,000-1/20,000 births, with a female predilection of 2:1. The disorder is caused by partial loss of material from the distal portion of the short arm of chromosome 4 (4p16.3), and is considered a contiguous gene syndrome. No...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Craniofacial Abnormalities

Share to Developmental Disabilities

Share to Infant

Share to Infant, Newborn

Share to Nervous System

Share to Pregnancy

Source

Identifiers

PMID: 18932224
DOI: 10.1002/ajmg.c.30187

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Update on the clinical features and natural history of Wolf-Hirschhorn (4p-) syndrome: experience with 87 patients and recommendations for routine health supervision.PMID 18932224Read ↗

Natural history study of adults with Wolf-Hirschhorn syndrome 1: Case series of personally observed 35 individuals.Semantic proximity Read ↗

Wolf-Hirschhorn (4p-) syndrome.Semantic proximity Read ↗

Wolf-Hirschhorn syndrome: A case series from India.Semantic proximity Read ↗

Clinical features in adult patient with Wolf-Hirschhorn syndrome.Semantic proximity Read ↗

On the nosology and pathogenesis of Wolf-Hirschhorn syndrome: genotype-phenotype correlation analysis of 80 patients and literature review.Semantic proximity Read ↗

[Wolf-Hirschhorn syndrome. Description of a Spanish cohort of 51 cases and a literature review].Semantic proximity Read ↗

Natural history study of adults with Wolf-Hirschhorn syndrome 2: Patient-reported outcomes study.Semantic proximity Read ↗

Wolf-Hirschhorn syndrome (WHS) - literature review on the features of the syndrome.Semantic proximity Read ↗

[Wolf-Hirschhorn syndrome. A series of 27 patients: their epidemiological and clinical characteristics. The current situation of the patients and the opinions of their caregivers regarding the diagnostic process].Semantic proximity Read ↗

Wolf-Hirschhorn Syndrome: Clinical and Genetic Study of 7 New Cases, and Mini ReviewSemantic proximity Read ↗

Prenatal phenotype of Wolf-Hirschhorn syndrome: A case series and literature review.Semantic proximity Read ↗

Mapping the Wolf-Hirschhorn syndrome phenotype outside the currently accepted WHS critical region and defining a new critical region, WHSCR-2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.