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Differential Activity of Repurposed Drugs as Receptor Binding Domain Antagonists for <i>Omicron</i> and Native Strains of SarsCov2

2022-03-09

Abstract excerpt

Omicron strain is the latest variant of concern of SarsCov2 virus. The mutations in this strain in the S protein Receptor Binding domain (RBD) enable it to be more transmissible as well as escape neutralizing activity by antibodies in response to vaccine. Thus, Omicron specific strategies are need to counter infection by this strain. We investigated a collection of approved drugs shown to antagonize the binding of...

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Literature Corpus work
43c5aa1d-243c-5dd0-bd6b-a205ecdc8961
DOI
10.1101/2022.03.09.483630
Open publication

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Differential Activity of Repurposed Drugs as Receptor Binding Domain Antagonists for <i>Omicron</i> and Native Strains of SarsCov2DOI 10.1101/2022.03.09.483630
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