Article

CONSENT: Scalable long read self-correction and assembly polishing with multiple sequence alignment

2019-02-11

Abstract excerpt

<h4>Motivation</h4> Third-generation sequencing technologies Pacific Biosciences and Oxford Nanopore allow the sequencing of long reads of tens of kbp, that are expected to solve various problems, such as contig and haplotype assembly, scaffolding, and structural variant calling. However, they also display high error rates that can reach 10 to 30%, for basic ONT and non-CCS PacBio reads. As a result, error correc...

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Literature Corpus work: 43b98a16-b685-5bd4-935c-f8ec8715d9aa
DOI: 10.1101/546630

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