Back to search

Article

Genomics‐Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic <i>Burkholderia</i> Species

2012-10-10

Abstract excerpt

Geheimnis gelüftet: Der Promotoraustausch in einem kryptischen Biosynthese-Gencluster, das in bestimmten pathogenen Burkholderia-Arten konserviert ist, führte zu einem instabilen, strukturell beispiellosen Polyketid (1). Markierungs- und Geninaktivierungs-Experimente sowie Bioinformatik-Analysen liefern erste Erkenntnisse zu einem faszinierenden Polyketid-Syntheseweg.

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4395b045-954a-5920-95b9-7e70dfe0420c
DOI
10.1002/ange.201205566
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genomics‐Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic <i>Burkholderia</i> SpeciesDOI 10.1002/ange.201205566
Genomics‐Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic <i>Burkholderia</i> SpeciesSemantic proximity
Burkholderia as a Source of Natural ProductsSemantic proximity
Ecological Diversity, Metabolic Versatility, and Biotechnological Applications of Burkholderia Species: An OverviewSemantic proximity
Computer-Aided Design of Agents That Inhibit the <i>cep</i> Quorum-Sensing System of <i>Burkholderia cenocepacia</i>Semantic proximity
Biotechnology approaches for natural product discovery, engineering, and production based on Burkholderia bacteriaSemantic proximity
A system for the construction of targeted unmarked gene deletions in the genus BurkholderiaSemantic proximity
The Genome of <i>Burkholderia cenocepacia</i> J2315, an Epidemic Pathogen of Cystic Fibrosis PatientsSemantic proximity
Molecular signatures and phylogenomic analysis of the genus Burkholderia: proposal for division of this genus into the emended genus Burkholderia containing pathogenic organisms and a new genus Paraburkholderia gen. nov. harboring environmental speciesSemantic proximity
A broad-host-range CRISPRi toolkit for silencing gene expression in <i>Burkholderia</i>Semantic proximity
Biotechnology of polyketides: new breath of life for the novel antibiotic genetic pathways discovery through metagenomicsSemantic proximity
Complete Genome Sequences for 59 <i>Burkholderia</i> Isolates, Both Pathogenic and Near NeighborSemantic proximity
Comparative genome‐wide analysis reveals that <i>Burkholderia contaminans</i> <scp>MS</scp> 14 possesses multiple antimicrobial biosynthesis genes but not major genetic loci required for pathogenesisSemantic proximity
Select a neighboring publication to make it the new centre.