Article

MicroRNA-29 regulates tumor progression and survival through miR-29a-SIRT1-Wnt/β-catenin pathway in hepatocellular carcinoma

2023-04-05

Abstract excerpt

Sirtuin 1 (SIRT1) participates in the initiation and evolution of hepatocellular carcinoma (HCC). However, the specific mechanism of SIRT1 in HCC remains unsolved. The mRNA expression of miR-29a in HCC were identified by qRT-PCR. miR-29a mimic and inhibitor were employed. The alteration of biological behavior was evaluated by CCK8, clone formation, Transwell and wound-healing assay. SIRT1 was verified to be a targ...

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Literature Corpus work: 43597ff3-cf54-545e-b0b0-f621de34fbd9
DOI: 10.21203/rs.3.rs-2773899/v1

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