Article

Subchondral Bone Metabolic Responses to Acute Mechanical Loading in Unilateral Knee Pain: A Quantitative [ <sup>18</sup> F]NaF PET/MRI Study

2026-08-10

Abstract excerpt

<h4>Objective</h4> To characterize regional subchondral bone metabolism before and after acute mechanical loading in individuals with unilateral knee pain using dynamic [ 18 F]sodium fluoride ([ 18 F]NaF) positron emission tomography (PET)/magnetic resonance imaging (MRI), and to investigate relationships with cartilage composition and pain severity. <h4>Design</h4> Twenty-two individuals with unilateral knee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 432eb81a-48ad-597f-8cc5-756662f39a03
DOI: 10.64898/2026.08.07.26359981

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Subchondral Bone Metabolic Responses to Acute Mechanical Loading in Unilateral Knee Pain: A Quantitative [ <sup>18</sup> F]NaF PET/MRI StudyDOI 10.64898/2026.08.07.26359981Read

Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI.Semantic proximity Read

Altered Subchondral Bone Mineral Density in Painful Knee Osteoarthritis Without Cysts: A Comparative Analysis of Lateral and Medial RegionsSemantic proximity Read

Exploring healthy knee kinematic phenotypes obtained through dynamic CT imaging: A cluster analysis study.Semantic proximity Read

Fat infiltration in the vastus medialis implicates joint structural abnormalities in early-stage symptomatic knee osteoarthritisSemantic proximity Read

Evaluation of Bone Metabolic Activity in the Spine with 18 F-FDG and 18 F-NaF PET/CT Imaging: Associations with Degenerative Risk FactorsSemantic proximity Read

Cartilage mechanical responses during gait as in silico biomarkers for medial knee OA progressionSemantic proximity Read

Modeling the role of ATP metabolism in articular cartilage and osteoarthritisSemantic proximity Read

Pain imaging in the emerging era of molecular medicine.Semantic proximity Read

New developments in osteoarthritis. Sex differences in magnetic resonance imaging-based biomarkers and in those of joint metabolismSemantic proximity Read

Identification of Pain-Associated Effusion-Synovitis from Knee Magnetic Resonance Imaging by Deep Generative NetworksSemantic proximity Read

MRI-derived Articular Cartilage Strains Predict Patient-Reported Outcomes Six Months Post Anterior Cruciate Ligament ReconstructionSemantic proximity Read

Tissue material properties and computational modelling of the human knee: A critical reviewSemantic proximity Read