Article

Engineered Antiviral Sensor Targets Infected Mosquitoes

2023-01-27

Abstract excerpt

Escalating vector disease burdens pose significant global health risks, so innovative tools for targeting mosquitoes are critical. We engineered an antiviral strategy termed REAPER (v R NA E xpression A ctivates P oisonous E ffector R ibonuclease) that leverages the programmable RNA-targeting capabilities of CRISPR Cas13 and its potent collateral activity. Akin to a stealthy Trojan Horse hiding in stealth aw...

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Literature Corpus work: 42d2a536-a2c2-5f89-a014-b143609ba52a
DOI: 10.1101/2023.01.27.525922

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