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The Role of CXCL12-Mediated Aberrant Methylation and Tumor Microenvironment Remodeling in Carcinogenesis and Prognosis of Bladder Cancer

2021-09-16

Abstract excerpt

<title>Abstract</title> <p>Background Bladder cancer (BLCA) is the most common genitourinary tumor but lacks specific diagnostic biomarkers. Recent years have seen significant advances in the use and approval of immune checkpoint blockade (ICB) therapy to manage bladder cancer at advanced stages when platinum-based therapy has failed. The tumor microenvironment (TME) in bladder cancer is an essential player in p...

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Literature Corpus work
418050fc-36f9-547e-8409-45730cf1567c
DOI
10.21203/rs.3.rs-882682/v1
Open publication

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