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The Predictive efficacy of tumor mutational burden for immune Checkpoint Inhibitors in non-small cell lung cancer: A systematic review and meta-analysis of randomized controlled trials

2025-08-20

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<title>Abstract</title> <p>Background: To date, immune checkpoint inhibitors (ICIs) have become the mainstay of treatment for locally advanced or metastatic non-small cell lung cancer (NSCLC). However, a subset of patients derives poor benefits from ICIs, highlighting the need for reliable biomarkers to identify those who are more likely to respond to such therapies. This review aims to evaluate the role of tumor...

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Literature Corpus work
41504573-7464-55de-bc73-6a6d6a370e24
DOI
10.21203/rs.3.rs-7114203/v1
Open publication

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