Article

Transcriptomic Profiling Reveals Predictive Markers of Response to Concurrent Chemoradiotherapy plus Immune Checkpoint Inhibition in Cervical Cancer

2025-08-13

Abstract excerpt

<title>Abstract</title> <p>Background Concurrent chemoradiotherapy (CCRT) combined with immune checkpoint inhibition has emerged as a promising treatment for locally advanced cervical cancer (LACC), yet approximately 30% of patients fail to achieve complete response. Methods Here, we performed RNA sequencing on pretreatment biopsies from 71 LACC patients treated with CCRT plus toripalimab to identify transcriptom...

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Literature Corpus work: 40f9cf5b-9c75-5826-aa65-d31a8278c933
DOI: 10.21203/rs.3.rs-7266839/v1

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