Article

Cervical cancer stem-like cell transcriptome profiles predict response to chemoradiotherapy

2020-11-04

Abstract excerpt

<h4>ABSTRACT</h4> Cervical cancer (CC) represents a major global health issue, particularly impacting women from resource constrained regions worldwide. Treatment refractoriness to standard chemo-radiotherapy has identified cancer stem cells as critical coordinators behind the biological mechanisms of resistance, contributing to CC recurrence. In this work, we evaluated differential gene expression in cervical can...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2286f3ba-7d70-587f-92d2-dc9b14c21471
DOI: 10.1101/2020.11.03.20223339

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cervical cancer stem-like cell transcriptome profiles predict response to chemoradiotherapyDOI 10.1101/2020.11.03.20223339Read

Cervical cancer stem cell‑associated genes: Prognostic implications in cervical cancer (Review)Semantic proximity Read

Novel marker genes and small molecule drugs for radiotherapy resistance in cervical cancer identified based on single-cell multi-omics analysisSemantic proximity Read

Establishment of a Prognostic Stemness Signature For Cervical Squamous Cell CarcinomaSemantic proximity Read

Transcriptomic Profiling Reveals Predictive Markers of Response to Concurrent Chemoradiotherapy plus Immune Checkpoint Inhibition in Cervical CancerSemantic proximity Read

Decoding the tumor microenvironment and molecular mechanism: unraveling cervical cancer subpopulations and prognostic signatures through scRNA-Seq and bulk RNA-seq analysesSemantic proximity Read

Identification of immune-related therapeutically relevant biomarkers in breast cancer and breast cancer stem cells by transcription-wide analysis: a clinical prospective studySemantic proximity Read

Single-Cell RNA Sequencing Reveals Multiple Pathways and the Tumor Microenvironment Could Lead to Chemotherapy Resistance in Cervical CancerSemantic proximity Read

Integrating single-cell and bulk RNA sequencing data identifies hypoxia as a predictive signature in cervical cancerSemantic proximity Read

Single‐Nucleus Transcriptome Profiling of Locally Advanced Cervical Squamous Cell Cancer Identifies Neural‐Like Progenitor Program Associated with the Efficacy of RadiotherapySemantic proximity Read

A novel DNA damage repair-related gene signature predicting survival, immune infiltration and drug sensitivity in cervical cancer based on single cell sequencingSemantic proximity Read

Cancer-Associated Stemness and Epithelial-to-Mesenchymal Transition Signatures Related to Breast Invasive Carcinoma PrognosticSemantic proximity Read

Cervical cancer stem cells: opportunities and challengesSemantic proximity Read