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Transcriptomics-based subphenotyping of the human placenta enabled by weighted correlation network analysis in early-onset preeclampsia with and without fetal growth restriction

2023-03-12

Abstract excerpt

<h4>Background: </h4> Placental disorders contribute to pregnancy complications, including preeclampsia (PE) and fetal growth restriction (FGR), but debate regarding their specific pathobiology persists. Our objective was to apply transcriptomics with weighted gene correlation network analysis (WGCNA) to further clarify the placental dysfunction in these conditions. <h4>Methods:</h4> We performed RNA sequencing wi...

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Literature Corpus work
40b4d644-fad3-5311-b09c-66dcb3e10320
DOI
10.1101/2023.03.08.23286998
Open publication

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Transcriptomics-based subphenotyping of the human placenta enabled by weighted correlation network analysis in early-onset preeclampsia with and without fetal growth restrictionDOI 10.1101/2023.03.08.23286998
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