Article

Omega-3 Fatty Acid DHA Induces Ferroptosis in Colorectal Cancer Patient-Derived Organoids and Drug-Tolerant Cells

2026-01-16

Abstract excerpt

<title>Abstract</title> <p>Several epidemiological and preclinical studies suggest that omega-3 (n-3) polyunsaturated fatty acids (PUFAs) exert anticancer activity at multiple stages of colorectal cancer (CRC) progression. However, inconsistent clinical evidence and the lack of a defined molecular mechanism underlying the antitumoral effects of n-3 PUFAs have raised doubts about their efficacy as adjuvant antican...

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Literature Corpus work: 3ff981bc-2631-56e2-9846-f5909c4a5f8e
DOI: 10.21203/rs.3.rs-8502020/v1

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