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DeepEXPOKE: A Deep Learning Framework with Polygenic Risk Scores as Knockoffs for Deconvoluting Genetic and Non-Genetic Exposure Risks in Sepsis and Coronary Heart Disease

2024-10-16

Abstract excerpt

<h4>ABSTRACT</h4> The exposome refers to the totality of environmental, behavioral, and lifestyle exposures an individual experiences throughout one’s lifetime. Due to the modifiability of exposures, identifying the risk exposures on a disease is crucial for effective intervention and prevention of the disease. However, traditional analytical methods struggle to capture the complexities of exposome data: nonlinear...

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Literature Corpus work: 3fd6d380-20e4-5435-ad77-27c8d2ef4efc
DOI: 10.1101/2024.10.15.24315572

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