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Article

BDKANN - Biological Domain Knowledge-based Artificial Neural Network for drug response prediction

2019-11-13

Abstract excerpt

<h4>Motivation</h4> One of the main goals of precision oncology is to predict the response of a patient to a given cancer treatment based on their genomic profile. Although current models for drug response prediction are becoming more accurate, they are also ‘black boxes’ and cannot explain their predictions, which is of particular importance in cancer treatment. Many models also do not leverage prior biological...

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Literature Corpus work
3f71d15c-aad2-52de-9b4b-f4a600a6135a
DOI
10.1101/840553
Open publication

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