Article
Deep learning and multi-omics approach to predict drug responses in cancer.
BMC bioinformatics - 28 Nov 2022
Wang Conghao, Lye Xintong, Kaalia Rama, Kumar Parvin, Rajapakse Jagath C
Abstract excerpt
BACKGROUND: Cancers are genetically heterogeneous, so anticancer drugs show varying degrees of effectiveness on patients due to their differing genetic profiles. Knowing patient's responses to numerous cancer drugs are needed for personalized treatment for cancer. By using molecular profiles of cancer cell lines available from Cancer Cell Line Encyclopedia (CCLE) and anticancer drug responses available in the...
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