Article

Epistatic interaction of PDE4DIP and DES mutations in familial atrial fibrillation with slow conduction

2021-01-19

Abstract excerpt

Background: The genetic causes of atrial fibrillation (AF) with slow conduction are unknown. <h4>Methods:</h4> Eight kindreds with familial AF and slow conduction, including a family affected by early onset AF, heart block and incompletely penetrant non-ischemic cardiomyopathy (NICM) underwent whole exome sequencing. <h4>Results:</h4> A known pathogenic mutation in the desmin ( DES ) gene resulting in S13F substi...

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Literature Corpus work: 3eed6529-4e30-5e5b-aff5-9bd7e7db1574
DOI: 10.22541/au.161109884.43570882/v1

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