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Analysis of Genomes and Transcriptomes of Clear Cell Renal Cell Carcinomas Identifies Mutations and Gene Expression Changes in TGF-beta Pathway

2022-04-11

Abstract excerpt

The occurrence of clear cell renal cell carcinoma (ccRCC) is related to the change of transforming growth factor-β (TGF-β) signal pathway. We adopted an integrated approach to identify and verify the effects of changes in this pathway in ccRCC, and provide direction for finding new therapeutic targets. We performed transcriptome analysis on 539 cases of ccRCC from The Cancer Genome Atlas (TCGA) and divided the sam...

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Literature Corpus work
3e3d50f2-6ed5-576d-94f9-edcd2e5bbda6
DOI
10.21203/rs.3.rs-1525653/v1
Open publication

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Analysis of Genomes and Transcriptomes of Clear Cell Renal Cell Carcinomas Identifies Mutations and Gene Expression Changes in TGF-beta PathwayDOI 10.21203/rs.3.rs-1525653/v1
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