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Patient Stratification of Clear Cell Renal Cell Carcinoma Using the Global Transcription Factor Activity Landscape Derived From RNA-Seq Data

4 Dec 2020

Abstract excerpt

Clear cell renal cell carcinoma represents the most common type of kidney cancer. Precision medicine approach to ccRCC requires an accurate stratification of patients that can predict prognosis and guide therapeutic decision. Transcription factors are implicated in the initiation and progression of human carcinogenesis. However, no comprehensive analysis of transcription factor activity has been proposed so far...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33344220
DOI: 10.3389/fonc.2020.526577

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