Article

Kounis Syndrome in the Modern Era: A Comprehensive Review of Allergic Acute Coronary Syndromes

2026-07-28

Abstract excerpt

Kounis syndrome (KS) is an increasingly recognized cause of acute coronary syndromes triggered by allergic or hypersensitivity reactions. The syndrome results from a complex interplay between mast-cell degranulation and platelet activation during allergic reactions, leading to the release of vasoactive, pro-inflammatory and prothrombotic mediators. These mechanisms may induce coronary vasospasm (type I KS) or thro...

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Literature Corpus work: 3e30b70e-c534-52d8-b1ab-47b395e32dcd
DOI: 10.20944/preprints202607.2027.v1

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