Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coronary artery abnormalities in Hyper-IgE syndrome.

Journal of clinical immunology - 1 Jun 2011

Freeman Alexandra F, Avila Elizabeth Mannino, Shaw Pamela A, Davis Joie, Hsu Amy P, Welch Pamela, Matta Jatin R, Hadigan Colleen, Pettigrew Roderic I, Holland Steven M, Gharib Ahmed M

Abstract excerpt

OBJECTIVE: Hyper-IgE syndrome (HIES) is a rare primary immunodeficiency caused by autosomal dominant STAT3 mutations resulting in recurrent infections and connective tissue abnormalities. Coronary artery abnormalities have been reported infrequently. We aimed to determine the frequency and characteristics of coronary artery abnormalities. DESIGN: STAT3-mutated HIES patients (n=38), ranging in age from 8 to 57...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Angiography
Share to Coronary Artery Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Coronary Vessels

Share to Genes, Dominant

Share to Job Syndrome

Share to Magnetic Resonance Angiography

Share to STAT3 Transcription Factor

Share to Tomography, X-Ray Computed

Source

Open in PubMed Open full text

Identifiers

PMID: 21494893
DOI: 10.1007/s10875-011-9515-9
PMCID: PMC4091041

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coronary artery abnormalities in Hyper-IgE syndrome.PMID 21494893Read ↗

Hyper-IgE syndrome update.Semantic proximity Read ↗

Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency.Semantic proximity Read ↗

Kounis Syndrome in the Modern Era: A Comprehensive Review of Allergic Acute Coronary SyndromesSemantic proximity Read ↗

Pathogenesis of hyper IgE syndrome.Semantic proximity Read ↗

Analysis of Traditional Risk Factors of Atherosclerosis and Novel Risk Markers of Inflammation in Coronary Ectasia Can We Solve The Enigma ??Semantic proximity Read ↗

Molecular and cellular insights into the pathogenesis of coronary artery ectasia.Semantic proximity Read ↗

Coronary microvascular dysfunction: Phenotype-specific targeted therapies.Semantic proximity Read ↗

Dilated coronary arteries in a 2-month-old with RIT1-associated Noonan syndrome: a case report.Semantic proximity Read ↗

Severe epistaxis due to aberrant vasculature in a patient with STAT-1 mutation.Semantic proximity Read ↗

Images in cardiovascular medicine. Arterial tortuosity syndrome: phenotypic features and cardiovascular manifestations.Semantic proximity Read ↗

Cerebral aneurysm in a 12-year-old boy with a STAT3 mutation (hyper-IgE syndrome).Semantic proximity Read ↗

Broadening the clinical spectrum of giant cell arteritis: from the classic cranial to the predominantly extracranial pattern of the disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.