Article

Metabolic modeling reveals a multi-level deregulation of host-microbiome metabolic networks in IBD

2024-09-19

Abstract excerpt

Inflammatory bowel diseases (IBDs) are chronic disorders involving dysregulated immune responses. Despite the role of disrupted host-microbial interaction in the pathophysiology of IBD, the underlying metabolic principles are not fully understood. We densely profiled microbiome, transcriptome and metabolome signatures from longitudinal IBD cohorts before and after advanced drug therapy initiation and reconstructed...

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Literature Corpus work: 3b7c574d-3abe-5452-b83a-8fc24d671b8b
DOI: 10.1101/2024.09.16.613185

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