Article

<i>ZFHX3</i>variants cause childhood partial epilepsy and infantile spasms with favorable outcomes

2023-07-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The ZFHX3 gene plays vital roles in embryonic development, cell proliferation, neuronal differentiation, and neuronal death. This study aims to explore the relationship between ZFHX3 variants and epilepsy. <h4>Methods</h4> Whole-exome sequencing was performed in a cohort of 378 patients with partial (focal) epilepsy. A Drosophila Zfh2 knockdown model was used to validate the a...

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Literature Corpus work: 3b7c2d95-1d11-55cc-977b-84855c3990b6
DOI: 10.1101/2023.07.16.23292551

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