Article

Directed evolution of bacteriophages: impacts of prolific prophage

2024-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Various directed evolution methods exist that seek to procure bacteriophages with expanded host ranges, typically targeting phage-resistant or non-permissive bacterial hosts. The general premise of these methods is to propagate phage on multiple bacterial hosts, pool the lysate, and repeat the propagation process until phage(s) can form plaques on the target host(s). In theory, this propagation...

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Literature Corpus work: 3b705d6c-605b-5d7b-83fb-c029bfe44f5a
DOI: 10.1101/2024.06.28.601269

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