Article

Biochemical characterization and barrier-disrupting mechanism of TsATG4B, a C54 cysteine protease of Trichinella spiralis, underlying larval intestinal invasion

2026-07-27

Abstract excerpt

<title>Abstract</title> Trichinellosis is a globally prevalent zoonotic parasitic disease, and cysteine proteases (CPs) secreted by <italic>Trichinella spiralis</italic> are critical virulence effectors that facilitate larval invasion into the host intestinal epithelium. Our previous study identified autophagy-related protease 4B (ATG4B) as a CP potentially involved in larval invasion. However, its detaile...

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Literature Corpus work: 3b6f58ee-495e-5f0c-8aaa-10ea2f40371e
DOI: 10.21203/rs.3.rs-10363990/v1

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Biochemical characterization and barrier-disrupting mechanism of TsATG4B, a C54 cysteine protease of Trichinella spiralis, underlying larval intestinal invasionDOI 10.21203/rs.3.rs-10363990/v1Read

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