Article

Immunogenicity of Convalescent and Vaccinated Sera Against Clinical Isolates of Ancestral SARS-CoV-2, Beta, Delta, and Omicron Variants

2022-02-10

Abstract excerpt

The omicron variant of concern (VOC) of SARS-CoV-2 was first reported in November 2021 in Botswana and South Africa. Omicron has evolved multiple mutations within the spike protein and the receptor binding domain (RBD), raising concerns of increased antibody evasion. Here, we isolated infectious omicron from a clinical specimen obtained in Canada. The neutralizing activity of sera from 65 coronavirus disease (COVI...

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Literature Corpus work: 3b6aea77-7fde-5896-a069-c3f6d9e83915
DOI: 10.2139/ssrn.4032071

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