Article
Considerable escape of SARS-CoV-2 Omicron to antibody neutralization.
Nature - 1 Feb 2022
Planas Delphine, Saunders Nell, Maes Piet, Guivel-Benhassine Florence, Planchais Cyril, Buchrieser Julian, Bolland William-Henry, Porrot Françoise, Staropoli Isabelle, Lemoine Frederic, Péré Hélène, Veyer David, Puech Julien, Rodary Julien, Baele Guy, Dellicour Simon, Raymenants Joren, Gorissen Sarah, Geenen Caspar, Vanmechelen Bert, Wawina-Bokalanga Tony, Martí-Carreras Joan, Cuypers Lize, Sève Aymeric, Hocqueloux Laurent, Prazuck Thierry, Rey Félix A, Simon-Loriere Etienne, Bruel Timothée, Mouquet Hugo, André Emmanuel, Schwartz Olivier
Abstract excerpt
The SARS-CoV-2 Omicron variant was first identified in November 2021 in Botswana and South Africa1-3. It has since spread to many countries and is expected to rapidly become dominant worldwide. The lineage is characterized by the presence of around 32 mutations in spike-located mostly in the N-terminal domain and the receptor-binding domain-that may enhance viral fitness and enable antibody evasion. Here we...
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