LINC1521 and miR-3679-5p modulate cellular response to chemical stress in breast cancer patients through regulation of XBP1 expression as a potential diagnostic biomarker

Abstract excerpt

<title>Abstract</title> <p>Background The majority of breast cancer (BC) patients die of metastasis rather than primary tumors, whereas the molecular mechanisms orchestrating cancer metastasis remains poorly understood. Long noncoding RNAs (lncRNA) have been shown to regulate cancer occurrence and progression. However, the lncRNAs that drive metastasis in cancer patients and their underlying mechanisms are still...

Topics

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• Brain Metastases and Treatment
• Cancer Cells and Metastasis
• Cancer, Hypoxia, and Metabolism
• Cancer-related Molecular Pathways
• Cytokine Signaling Pathways and Interactions
• Hippo pathway signaling and YAP/TAZ
• Lung Cancer Treatments and Mutations
• Radiopharmaceutical Chemistry and Applications

Identifiers and source

Literature Corpus work

3b4eb79e-5a12-56d7-884b-f597d99d74c3

DOI

10.21203/rs.3.rs-3252674/v1