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Development of a liquid biopsy for bladder cancer using a mutant protein panel in urinary extracellular vesicles

2025-05-13

Abstract excerpt

Non-muscle invasive bladder cancer often relapses after cystoscopic surgery, necessitating rigorous monitoring for recurrence through invasive and painful cystoscopy. To develop a novel non-invasive and cancer-specific diagnostic method, somatic mutant proteins in urinary extracellular vesicles (EVs) were for the first time investigated using a proteogenomics pipeline consisting of whole exome sequencing and LC/MS...

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Identifiers and source

Literature Corpus work
3b400e2b-6b3a-5ffa-b1f7-9dd03a969622
DOI
10.1101/2025.05.12.653366
Open publication

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Development of a liquid biopsy for bladder cancer using a mutant protein panel in urinary extracellular vesiclesDOI 10.1101/2025.05.12.653366
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