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Tumour tissue‐derived small extracellular vesicles reflect molecular subtypes of bladder cancer

31 Jan 2024

Abstract excerpt

mRNA-based molecular subtypes have implications for bladder cancer prognosis and clinical benefit from certain therapies. Whether small extracellular vesicles (sEVs) can reflect bladder cancer molecular subtypes is unknown. We performed whole transcriptome RNA sequencing for formalin fixed paraffin embedded (FFPE) tumour tissues and sEVs separated from matched tissue explants, urine and plasma in patients with...

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PMID: 38293707
DOI: 10.1002/jev2.12402

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