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Alpha-Gal Syndrome: Involvement of <i>Amblyomma americanum</i> α-D-galactosidase and α-1,4 Galactosyltransferase enzymes in α-gal metabolism

2021-09-13

Abstract excerpt

Alpha-Gal Syndrome (AGS) is an IgE-mediated delayed-type hypersensitivity reaction to the oligosaccharide galactose-⍰-1,3-galactose (α-gal) injected into humans from the lone star tick ( Amblyomma americanum ) bite. This study aims at the functional characterization of two tick enzymes, α-D-galactosidase (ADGal) and α-1,4 galactosyltransferase (β-1,4GalT) in α-gal metabolism. The ADGal enzyme cleaves terminal α-g...

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Literature Corpus work
3aac29c0-992a-59ba-b911-19cc4dce6b30
DOI
10.1101/2021.09.13.460140
Open publication

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Alpha-Gal Syndrome: Involvement of <i>Amblyomma americanum</i> α-D-galactosidase and α-1,4 Galactosyltransferase enzymes in α-gal metabolismDOI 10.1101/2021.09.13.460140
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