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SPOP promotes cervical cancer progress by inducing PD-1 move away from PD-L1 in spatial localization

2022-04-25

Abstract excerpt

<h4>Background: </h4> Metastasis is a major obstacle in treatment of cervical cancer (CC), and gene SPOP mediated regulatory effect is found to be involved in metastasis. However, its mechanisms have not been fully elucidated. Methods We performed proteomic sequencing, immunohistochemical staining (IHC) and scoring of SPOP in cancer tissues of 180 patients with 2009 FIGO stage IB1-IIA2 CC, and compared the expres...

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Literature Corpus work
3a8051b9-6cbb-5fe6-bacf-435610f178e2
DOI
10.21203/rs.3.rs-1535339/v1
Open publication

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SPOP promotes cervical cancer progress by inducing PD-1 move away from PD-L1 in spatial localizationDOI 10.21203/rs.3.rs-1535339/v1
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