Article

Patient-Derived Inner Ear Organoids as a Disease Modeling and Therapy Validation Platform For Hereditary Inner Ear Disorders

2026-07-20

Abstract excerpt

<h4>Background</h4> Hereditary inner ear disorders comprise a highly heterogenous group of disorders and are a major cause of hearing and vestibular dysfunction. Despite advances in genetic diagnosis, the development of precision therapies has been limited by the lack of relevant and scalable human model systems that can accommodate the wide spectrum of disease-causing variants and support the evaluation of thera...

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Literature Corpus work: 39d4940a-fb06-59c9-be90-6ece6ddb337c
DOI: 10.64898/2026.07.14.738390

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