Article

Predicting clinically promising therapeutic hypotheses using tensor factorization

2018-02-27

Abstract excerpt

<h4>ABSTRACT</h4> Determining which target to pursue is a challenging and error-prone first step in developing a therapeutic treatment for a disease, where missteps are potentially very costly given the long-time frames and high expenses of drug development. We identified examples of successes and failures of target-indication pairs in clinical trials across 875 targets and 574 disease indications to build a gold...

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Literature Corpus work: 39c34ceb-7198-5b59-8855-218e46b836f3
DOI: 10.1101/272740

Open publication

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