Article

Dynamical consequences of regional heterogeneity in the brain’s transcriptional landscape

2020-10-29

Abstract excerpt

Brain regions vary in their molecular and cellular composition, but how this heterogeneity shapes neuronal dynamics is unclear. Here, we investigate the dynamical consequences of regional heterogeneity using a biophysical model of whole-brain functional magnetic resonance imaging (MRI) dynamics in humans. We show that models in which transcriptional variations in excitatory and inhibitory receptor (E:I) gene expre...

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Literature Corpus work: 39547a4e-3578-5474-956f-11d8a7e4f943
DOI: 10.1101/2020.10.28.359943

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