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Article

Detection of Genetic Variations in Children with Tetralogy of Fallot Using Whole Exome Sequencing Technology Integrated Bioinformatics Analysis.

Genetic testing and molecular biomarkers - 1 Dec 2024

Abdullahi Khalid Mohamoud, Ali Ahmed Faisal, Adan Mohamed Mohamoud, Shu Qiang

Abstract excerpt

Background: Tetralogy of Fallot (TOF) is the most common cyanotic heart defect in newborns, with a complex etiology and genetic variation considered to be one of the main pathogenic factors. Identifying genetic variations associated with TOF has important clinical value for understanding its pathogenesis, patient susceptibility, and prognosis of patients with TOF. Therefore, this study aimed to identify potential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39653367
DOI: 10.1089/gtmb.2024.0350
PMCID: PMC11659463

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Detection of Genetic Variations in Children with Tetralogy of Fallot Using Whole Exome Sequencing Technology Integrated Bioinformatics Analysis.PMID 39653367Read ↗

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