Article

Neural Signatures of α2 Adrenergic Agonist-Induced Unconsciousness and Awakening by Antagonist

2020-04-23

Abstract excerpt

How the brain dynamics transition during anesthetic-induced altered states of consciousness is not completely understood. The α 2 adrenergic agonist is a unique anesthetic that generates unconsciousness selectively through α 2 adrenergic receptors and related circuits. We studied intracortical neuronal dynamics during transitions of loss of consciousness (LOC) with the α 2 adrenergic agonist dexmedetomidine and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 39097c11-d1f3-525b-b841-b5bc0e841bc6
DOI: 10.1101/2020.04.21.053330

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neural Signatures of α2 Adrenergic Agonist-Induced Unconsciousness and Awakening by AntagonistDOI 10.1101/2020.04.21.053330Read

A human intracranial map of consciousness returning from anesthesiaSemantic proximity Read

Early reactivation of medial temporal lobe neurons during emergence from propofol anesthesia in neurosurgical patientsSemantic proximity Read

Multimodal profiling reveals the centromedian nucleus of thalamus as a dynamic hub orchestrating staged consciousness recoverySemantic proximity Read

Neural signatures of loss of consciousness and its recovery by thalamic stimulationSemantic proximity Read

Mapping general anesthesia states based on electro-encephalogram transition phasesSemantic proximity Read

Registered report: Common signatures of loss of responsiveness in human and macaque electrocorticogramSemantic proximity Read

Registered report: Common signatures of loss of responsiveness in human and macaque electrocorticogramSemantic proximity Read

Quantitative assessment of the relationship between behavioral and autonomic dynamics during propofol-induced unconsciousnessSemantic proximity Read

Differential Cortical Network Engagement During States of Un/Consciousness in HumansSemantic proximity Read

An Electrophysiological Marker of Arousal Level in HumansSemantic proximity Read

Dexmedetomidine produces more sleep-like brain activity compared to propofolSemantic proximity Read

Paths to Oblivion: Common Neural Mechanisms of Anaesthesia and Disorders of ConsciousnessSemantic proximity Read