Article

Neural signatures of loss of consciousness and its recovery by thalamic stimulation

2019-10-17

Abstract excerpt

We know that general anesthesia produces unconsciousness but not quite how. We recorded neural activity from the frontal, parietal, and temporal cortices and thalamus while maintaining unconsciousness in non-human primates (NHPs) with propofol. Unconsciousness was marked by slow frequency (∼1 Hz) oscillations in local field potentials, entraining local spiking to Up states alternating with Down states of little sp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0f7ec7ad-9d4a-5281-896c-d74c9bd47b3f
DOI: 10.1101/806687

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neural signatures of loss of consciousness and its recovery by thalamic stimulationDOI 10.1101/806687Read

A human intracranial map of consciousness returning from anesthesiaSemantic proximity Read

Propofol Mediated Unconsciousness Disrupts Progression of Sensory Signals through the Cortical HierarchySemantic proximity Read

Propofol-induced loss of responsiveness reorganizes cortical traveling waves in the human brainSemantic proximity Read

General anaesthesia disrupts complex cortical dynamics in response to intracranial electrical stimulation in ratsSemantic proximity Read

Dynamic changes in rhythmic and arrhythmic neural signatures in the subthalamic nucleus induced by anaesthesia and intubationSemantic proximity Read

Criticality supports cross-frequency cortical-thalamic information transfer during conscious statesSemantic proximity Read

Distinct signatures of loss of consciousness during Focal Impaired Awareness versus Focal to Bilateral Tonic Clonic seizuresSemantic proximity Read

Registered report: Common signatures of loss of responsiveness in human and macaque electrocorticogramSemantic proximity Read

Registered report: Common signatures of loss of responsiveness in human and macaque electrocorticogramSemantic proximity Read

Early reactivation of medial temporal lobe neurons during emergence from propofol anesthesia in neurosurgical patientsSemantic proximity Read

Temporal changes in resting state networks induced by propofol anesthesiaSemantic proximity Read

Propofol disrupts alpha dynamics in distinct thalamocortical networks underlying sensory and cognitive function during loss of consciousnessSemantic proximity Read