Article

The Importance of Autosomal Genes in Kallmann Syndrome: Genotype-Phenotype Correlations and Neuroendocrine Characteristics

2001-04-01

Abstract excerpt

Kallmann syndrome (KS) consists of congenital, isolated, idiopathic hypogonadotropic hypogonadism (IHH) and anosmia.The gene responsible for the X-linked form of KS, KAL, encodes a protein, anosmin, that plays a key role in the migration of GnRH neurons and olfactory nerves to the hypothalamus.In addition to X-linked pedigrees, autosomal dominant and recessive kindreds with KS have been reported.The relative impor...

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Hypothalamic control of reproductive hormones

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Literature Corpus work: 3896a328-778a-5b10-94fe-a079825da79a
DOI: 10.1210/jc.86.4.1532

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