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Article

Defects in GnRH Neuron Migration/Development and Hypothalamic-Pituitary Signaling Impact Clinical Variability of Kallmann Syndrome.

Genes - 5 Jun 2021

Kałużna Małgorzata, Budny Bartłomiej, Rabijewski Michał, Kałużny Jarosław, Dubiel Agnieszka, Trofimiuk-Müldner Małgorzata, Wrotkowska Elżbieta, Hubalewska-Dydejczyk Alicja, Ruchała Marek, Ziemnicka Katarzyna

Abstract excerpt

Kallmann syndrome (KS) is a combination of isolated hypogonadotropic hypogonadism (IHH) with olfactory dysfunction, representing a heterogeneous disorder with a broad phenotypic spectrum. The genetic background of KS has not yet been fully established. This study was conducted on 46 Polish KS subjects (41 males, 5 females; average age: 29 years old). The studied KS patients were screened for defects in a 38-gene...

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Identifiers

PMID: 34198905
DOI: 10.3390/genes12060868
PMCID: PMC8229512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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