Article

Exploring the Transcriptional Crosstalk Between Adipose Tissue and Locoregional Recurrence in Breast Cancer Using Independent Component Analysis

2026-02-04

Abstract excerpt

<title>Abstract</title> <p> Background Locoregional recurrence (LRR) poses a persistent clinical challenge in breast cancer, with emerging evidence implicating the tumor-associated adipose tissue in modulating recurrence risk. This study investigates shared transcriptional programs between adipose tissue and breast tumors and examines their association with disease-free survival (DFS), particularly in the conte...

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Literature Corpus work: 3832f1f3-e947-5de8-ab0c-3143a7171a55
DOI: 10.21203/rs.3.rs-8544684/v1

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