Article
Integrative Comparison of mRNA Expression Patterns in Breast Cancers from Caucasian and Asian Americans with Implications for Precision Medicine.
Cancer research - 15 Jan 2017
Shi Yanxia, Steppi Albert, Cao Ye, Wang Jianan, He Max M, Li Liren, Zhang Jinfeng
Abstract excerpt
Asian Americans (AS) have significantly lower incidence and mortality rates of breast cancer than Caucasian Americans (CA). Although this racial disparity has been documented, the underlying pathogenetic factors explaining it are obscure. We addressed this issue by an integrative genomics approach to compare mRNA expression between AS and CA cases of breast cancer. RNA-seq data from the Cancer Genome Atlas showed...
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