Article

The landscape of human mutually exclusive splicing

2017-05-02

Abstract excerpt

Mutually exclusive splicing of exons is a mechanism of functional gene and protein diversification with pivotal roles in organismal development and diseases such as Timothy syndrome, cardiomyopathy and cancer in humans. In order to obtain a first genome-wide estimate of the extent and biological role of mutually exclusive splicing in humans we predicted and subsequently validated mutually exclusive exons (MXEs) us...

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Literature Corpus work: 37c3b3ae-0d7f-5329-8eec-226b4ef76e55
DOI: 10.1101/133215

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