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Article

The landscape of human mutually exclusive splicing.

Molecular systems biology - 14 Dec 2017

Hatje Klas, Rahman Raza-Ur, Vidal Ramon O, Simm Dominic, Hammesfahr Björn, Bansal Vikas, Rajput Ashish, Mickael Michel Edwar, Sun Ting, Bonn Stefan, Kollmar Martin

Abstract excerpt

Mutually exclusive splicing of exons is a mechanism of functional gene and protein diversification with pivotal roles in organismal development and diseases such as Timothy syndrome, cardiomyopathy and cancer in humans. In order to obtain a first genomewide estimate of the extent and biological role of mutually exclusive splicing in humans, we predicted and subsequently validated mutually exclusive exons (MXEs)...

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Identifiers

PMID: 29242366
DOI: 10.15252/msb.20177728
PMCID: PMC5740500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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