Article

Umbilical Cord Blood Cell Transcriptional and Methylation Signatures at Birth Are Associated with BPD Development

2025-11-05

Abstract excerpt

Bronchopulmonary dysplasia (BPD) is the most common respiratory disease in preterm infants born at less than 28 weeks gestation. Most existing clinical prediction models for BPD show limited accuracy in predicting BPD development when validated using external data, stressing the need for novel biomarkers to identify at-risk infants for early and effective interventions. We leveraged existing frozen umbilical cord...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 37ae5cbe-45ea-5afb-a215-0013c725b12c
DOI: 10.1101/2025.11.04.686323

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Umbilical Cord Blood Cell Transcriptional and Methylation Signatures at Birth Are Associated with BPD DevelopmentDOI 10.1101/2025.11.04.686323Read

Prospective epigenome and transcriptome analyses of cord and peripheral blood from preterm infants at risk of bronchopulmonary dysplasiaSemantic proximity Read

Epigenome-wide association study of bronchopulmonary dysplasia in preterm infants: results from the discovery-BPD programSemantic proximity Read

Lymphocyte-Specific Biomarkers Associated with Preterm Birth and Bronchopulmonary DysplasiaSemantic proximity Read

Lymphocyte-Specific Biomarkers Associated With Preterm Birth and Bronchopulmonary DysplasiaSemantic proximity Read

Identification of potential biomarkers in the peripheral blood of neonates with bronchopulmonary dysplasia using WGCNA and machine learning algorithmsSemantic proximity Read

Perturbation of gene expression of the chromatin remodeling pathway in premature newborns at risk for bronchopulmonary dysplasiaSemantic proximity Read

Analysis of two birth tissues provides new insights into the epigenetic landscape of neonates born pretermSemantic proximity Read

Single‐cell RNA sequencing of peripheral blood mononuclear cells from bronchopulmonary dysplasiaSemantic proximity Read

Bronchopulmonary Dysplasia Predicted by Developing a Machine Learning Model of Genetic and Clinical InformationSemantic proximity Read

Exome Sequencing of Neonatal Blood Spots and the Identification of Genes Implicated in Bronchopulmonary Dysplasia.Semantic proximity Read

Genomic and molecular characterization of preterm birthSemantic proximity Read

Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infantsSemantic proximity Read