Article

Heterozygous<i>KRT32</i>variant is responsible for autosomal dominant loose anagen hair syndrome

2025-05-06

Abstract excerpt

Loose Anagen Hair Syndrome is a form of non-scarring alopecia marked by easily and painlessly pluckable terminal hair during its active growth – anagen – phase. This condition is believed to result from poor hair shaft anchoring within the follicle due to premature keratinization. Our research identified the likely pathogenic c.296C>T (p.T99I) variant in KRT32 , which was found to co-segregate with the disorder in...

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Literature Corpus work: 37a7a84d-4919-5a4b-b907-d023cbfd3e18
DOI: 10.1101/2025.05.02.25326729

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